Bone Marrow Biopsy - Office

This procedure involves the removal of a small amount of bone marrow for examination.

This procedure involves the removal of a small amount of bone marrow for examination.

This procedure involves removing a small amount of bone marrow for examination. Bone marrow is located inside some of the bones in your body. It produces blood cells, including:

  • Red blood cells, which carry oxygen to the body's tissue and organs
  • White blood cells, which help fight infection and certain diseases
  • Platelets, which help control bleeding

Your healthcare provider may recommend a bone marrow biopsy if he or she is concerned with how these cells are developing and working.

A complete bone marrow examination includes a:

  • Bone marrow aspiration, which is when liquid bone marrow is drawn into a syringe. The area where the needle will be inserted is first injected with a numbing medication. Once numb, the doctor inserts a hollow needle into the bone (frequently the pelvic or hipbone) and the marrow is drawn up into a syringe.
  • Bone marrow biopsy, which is the removal of a small piece of solid bone marrow tissue. After the liquid bone marrow has been removed, a larger needle is guided into the bone to obtain a sample of the bone.
  • The samples are sent to the lab for examination (biopsy).

During the procedure, you may briefly feel a deep ache. You may also have a brief increase in pain when the bone marrow is being removed.

  • The pain will go away when the needle is removed.
  • The area where the bone marrow sample was obtained may be sore for a while.

Depending on the circumstances, a bone marrow biopsy can be done in a healthcare provider's office or operating room. This care path includes costs for a bone marrow biopsy that that is performed in a healthcare provider's office

What should I ask my healthcare provider before having a bone marrow biopsy?

  • What is the reason for the procedure? What happens if I do not go through with the procedure?
  • Are there any alternatives to this procedure?
  • Is there any special preparation for the procedure? (If so, get clear instructions on what you need to do.
  • Will you give me medication to make me sleepy (sedation)? If so, what kind of sedation will you use? What are the possible side effects?
  • What are the possible complications?
  • How will I feel after the procedure? Will I have to modify my activity?

After your procedure, you should know what you had done, what medication was given and what symptoms you should report to your healthcare provider.

  • You should also understand all home care instructions (including medications and side effects) and follow-up plans.
  • Do not forget to arrange for transportation to and from the facility and for help at home.


Also known as:

Bone Marrow Biopsy - Office
Bone Marrow Biopsy
Bone Marrow Aspiration
Biopsy Bone Marrow
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